Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | ACP3 | P15309 | 3/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805257 | 0.82 | PNMT (0.56) | PNMTCES2ACP3MRGPRX1IDO1 | |
| SCHEMBL6970288 | 0.81 | ACP3 (0.50) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL15331089 | 0.81 | ACP3 (0.50) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL19388859 | 0.79 | PNMT (0.53) | PNMTCES2ACP3MRGPRX1IDO1 | |
| SCHEMBL799866 | 0.79 | PNMT (0.53) | PNMTCES2ACP3MRGPRX1IDO1 | |
| SCHEMBL4135956 | 0.79 | PNMT (0.65) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL9570750 | 0.79 | ACP3 (0.47) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL6498675 | 0.79 | PNMT (0.51) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL17515119 | 0.79 | DAO (0.49) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL40176 | 0.79 | ACP3 (0.47) | PNMTCES2ACP3IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344460-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Galapagos N.V. (BE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010029119-A1 | NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | GALAPAGOS NV (BE) | 2010-03-18 | — | — | WO | disclosed |