Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | ACP3 | P15309 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135655 | 0.94 | PNMT (0.59) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL31067471 | 0.91 | TSHR (0.66) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL17073488 | 0.91 | TSHR (0.66) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL10889071 | 0.89 | PNMT (0.54) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL7626469 | 0.85 | PNMT (0.62) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL6154538 | 0.85 | CES2 (0.50) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL6155403 | 0.85 | PNMT (0.50) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL23021670 | 0.84 | PNMT (0.57) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL11201464 | 0.83 | KMT2A (0.54) | PNMTCES2ACP3IDO1TDO2 | |
| SCHEMBL11665754 | 0.83 | PNMT (0.49) | PNMTCES2ACP3IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | claimed |
| EP-0039903-B1 | 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF | SUNTORY KABUSHIKI KAISHA (JP) | 1986-04-09 | — | — | EP | claimed |
| EP-0039903-A2 | 8-Substituted pyrrolizidines and quaternary ammonium salts thereof | SUNTORY KABUSHIKI KAISHA (JP) | 1981-11-18 | — | — | EP | claimed |
| US-20230382775-A1 | METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION | ADIONICS (FR) | 2023-11-30 | — | — | US | disclosed |
| US-20230382775-A1 | METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION | ADIONICS (FR) | 2023-11-30 | — | — | US | disclosed |
| US-11772997-B2 | Method for extracting salts and temperature-regenerated extracting composition | ADIONICS (FR) | 2023-10-03 | — | — | US | disclosed |
| US-11772997-B2 | Method for extracting salts and temperature-regenerated extracting composition | ADIONICS (FR) | 2023-10-03 | — | — | US | disclosed |
| US-11731933-B2 | Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid | ADIONICS (FR) | 2023-08-22 | — | — | US | disclosed |
| US-11731933-B2 | Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid | ADIONICS (FR) | 2023-08-22 | — | — | US | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210355076-A1 | DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID | ADIONICS (FR) | 2021-11-18 | — | — | US | disclosed |
| WO-2008002583-A1 | GLYCINE TRANSPORTER-1 INHIBITORS | AMGEN INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| EP-1175424-A1 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000064906-A1 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |
| US-4792635-A | Symmetric benzophenones substituted by groups containing fluorine | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0156278-B1 | PROCESS FOR THE PREPARATION OF SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS, THEIR USE AND SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| US-4617401-A | ANTISPASMODIC AGENTS, VASODILATORS | SUNTORY LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
| EP-0039903-B1 | 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF | SUNTORY KABUSHIKI KAISHA (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0156278-A2 | Process for the preparation of symmetrical benzophenones substituted by fluor-containing groups, their use and symmetrical benzophenones substituted by fluor-containing groups | BAYER AG (DE) | 1985-10-02 | — | — | EP | disclosed |
| EP-0039903-A2 | 8-Substituted pyrrolizidines and quaternary ammonium salts thereof | SUNTORY KABUSHIKI KAISHA (JP) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731933-B2 | Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid | AQP3, AQP1, AQP4 | PNMT 1650/4885CES2 3361/4885ACP3 2533/4885 |
| US-20210355076-A1 | DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID | AQP3, AQP1, AQP4 | PNMT 1650/4885CES2 3361/4885ACP3 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.