SCHEMBL17124659

SCHEMBL17124659

C=C(C)C(=O)OCOC(=O)c1ccccc1-c1ccccc1C(=O)OCOC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.44
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 3/20 0.41
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HSD17B10 Q99714 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886899 0.92 TSHR (0.53) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL15713250 0.87 TSHR (0.53) TSHRALDH1A1CYP3A4SCN1ASCN2A
SCHEMBL8413374 0.86 TDP1 (0.54) TSHRALDH1A1TDP1L3MBTL1HSD17B10
SCHEMBL12181907 0.82 TSHR (0.51) TSHRALDH1A1CYP3A4SCN1ASCN2A
SCHEMBL18904535 0.82 CDC25B (0.52) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL2597547 0.82 TSHR (0.47) TSHRALDH1A1CYP3A4SCN1ASCN2A
SCHEMBL16193204 0.82 TSHR (0.47) TSHRALDH1A1TP53MAPTMEN1
SCHEMBL8453178 0.80 LMNA (0.51) TSHRALDH1A1TDP1L3MBTL1HSD17B10
SCHEMBL22058363 0.80 TSHR (0.45) TSHRALDH1A1CYP3A4SCN1ASCN2A
SCHEMBL6285566 0.79 SCN1A (0.59) TSHRALDH1A1CYP3A4SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170246302-A1 POLYMER COATING COMPOSITIONS AND COATED PRODUCTS ARISTE MEDICAL, LLC 2017-08-31 US disclosed
US-9605175-B2 Polymer coating compositions and coated products ARISTE MEDICAL, LLC (US) 2017-03-28 US disclosed
US-20160101219-A1 METHODS AND PROCESSES FOR APPLICATION OF DRUG DELIVERY POLYMERIC COATINGS ARISTE MEDICAL, INC. 2016-04-14 US disclosed
US-20150275026-A1 POLYMER COATING COMPOSITIONS AND COATED PRODUCTS ARISTE MEDICAL, LLC 2015-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150275026-A1 POLYMER COATING COMPOSITIONS AND COATED PRODUCTS PUF60, CUTA, CAPG TSHR 4625/4885ALDH1A1 3540/4885CYP3A4 3313/4885
US-20170246302-A1 POLYMER COATING COMPOSITIONS AND COATED PRODUCTS PUF60, CUTA, CAPG TSHR 4625/4885ALDH1A1 3540/4885CYP3A4 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.