SCHEMBL17126975

SCHEMBL17126975

CCOCCSC(C(=O)c1ccc(Oc2ccc(OC)cc2OC)cc1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.39
▸ MAPT P10636 2/20 0.36
▸ TSHR P16473 2/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ HTT P42858 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ APP P05067 1/20 0.36
▸ NPC1 O15118 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CYSLTR2 Q9NS75 1/20 0.34
▸ CYSLTR1 Q9Y271 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17126983 0.90 SMN1; SMN2 (0.36) MAPTTSHRMAPK1HPGDSMN1; SMN2
SCHEMBL17126973 0.88 SMN1; SMN2 (0.43) MAPTMAPK1HPGDSMN1; SMN2HTT
SCHEMBL17127023 0.88 KDM4E (0.37) MAPTMAPK1SMN1; SMN2HTTNPSR1
SCHEMBL17126862 0.88 AKR1C3 (0.39) HPGDSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL15935680 0.87 SMN1; SMN2 (0.46) MAPTMAPK1HPGDSMN1; SMN2HTT
SCHEMBL17126864 0.87 SCN9A (0.33) MAPTTSHRHPGDSMN1; SMN2NPC1
SCHEMBL17126857 0.83 APP (0.36) MAPTTSHRHPGDSMN1; SMN2HTT
SCHEMBL17127021 0.82 KDM4E (0.34) MAPTTSHRMAPK1HPGDSMN1; SMN2
SCHEMBL17127019 0.82 LMNA (0.41) MAPTHPGDSMN1; SMN2HTTNPSR1
SCHEMBL17127350 0.81 HIF1A (0.39) MAPTSMN1; SMN2HTTAPPNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150277225-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM FORMED USING SAID COMPOSITION, METHOD FOR FORMING PATTERN USING SAID COMPOSITION, PROCESS FOR PRODUCING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE TERB1, ACTR5, ADPRS TTR 2210/4885MAPT 995/4885TSHR 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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