Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782458 | 0.82 | BDKRB1 (0.65) | BDKRB1CNR1 | |
| SCHEMBL1713064 | 0.79 | BDKRB1 (0.56) | BDKRB1CNR1 | |
| SCHEMBL1713145 | 0.78 | BDKRB1 (0.81) | BDKRB1CNR1 | |
| SCHEMBL5782125 | 0.73 | BDKRB1 (0.63) | BDKRB1CNR1 | |
| SCHEMBL1712485 | 0.72 | BDKRB1 (0.63) | BDKRB1CNR1 | |
| SCHEMBL12239061 | 0.70 | CYP3A4 (0.40) | BDKRB1CNR1 | |
| SCHEMBL765124 | 0.70 | PTGER4 (0.44) | — | |
| SCHEMBL765182 | 0.68 | L3MBTL1 (0.41) | BDKRB1 | |
| SCHEMBL1712893 | 0.68 | BDKRB1 (0.71) | BDKRB1CNR1 | |
| SCHEMBL5783113 | 0.67 | BDKRB1 (0.52) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | claimed |
| WO-2010031577-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | JERINI AG (DE) | 2010-03-25 | — | — | WO | claimed |
| EP-2344176-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | Jerini AG (DE) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010031577-A1 | USE OF BRADYKININ B1 RECEPTOR ANTAGONISTS IN INTESTINAL FIBROSIS TREATMENT | JERINI AG (DE) | 2010-03-25 | — | — | WO | disclosed |