Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204456 | 0.82 | CA1 (0.52) | CA1CA2CA9KDM4EELANE | |
| SCHEMBL32665346 | 0.82 | CA1 (0.47) | CA1CA2CA9ELANEACHE | |
| SCHEMBL6937925 | 0.82 | CA1 (0.55) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL11160716 | 0.80 | CA1 (0.48) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL4131406 | 0.80 | CA1 (0.48) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL19348578 | 0.80 | CA2 (0.75) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL2989290 | 0.79 | CA1 (0.44) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL31195498 | 0.79 | CA1 (0.44) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL11655554 | 0.78 | CA1 (0.47) | CA1CA2CA9KDM4ESTS | |
| SCHEMBL32665524 | 0.78 | CA1 (0.47) | CA1CA2CA9ELANEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190177265-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW AGROSCIENCES LLC (US) | 2019-06-13 | — | — | US | disclosed |
| EP-3122707-B1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20170240499-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW GLOBAL TECHNOLOGIES LLC | 2017-08-24 | — | — | US | disclosed |
| US-20170240499-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW GLOBAL TECHNOLOGIES LLC | 2017-08-24 | — | — | US | disclosed |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW AGROSCIENCES LLC | 2017-07-27 | — | — | US | disclosed |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW AGROSCIENCES LLC | 2017-07-27 | — | — | US | disclosed |
| US-20170174582-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | DOW AGROSCIENCES LLC | 2017-06-22 | — | — | US | disclosed |
| US-20170174582-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | DOW AGROSCIENCES LLC | 2017-06-22 | — | — | US | disclosed |
| WO-2016057770-A1 | METHOD FOR COUPLING A FLUOROSULFONATE COMPOUND WITH AN AMINE COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016057771-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-14 | — | — | WO | disclosed |
| WO-2015148931-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174582-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | PAH, TYR, AHR | CA1 4564/4885CA2 3857/4885CA9 2039/4885 |
| US-20190177265-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | PAICS, NUDT21, TIAL1 | CA1 2107/4885CA2 3019/4885CA9 910/4885 |
| US-20170210695-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | PAICS, NUDT21, TIAL1 | CA1 2107/4885CA2 3019/4885CA9 910/4885 |
| US-20170240499-A1 | METHOD FOR COUPLING A FIRST COMPOUND TO A SECOND COMPOUND | SQLE, FDPS, PAICS | CA1 2285/4885CA2 2991/4885CA9 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.