SCHEMBL1713019

SCHEMBL1713019

C#Cc1c(-c2ccccc2)ccc2c1C(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
ALOX15 P16050 1/20 0.39
CTRC Q99895 2/20 0.36
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP19A1 P11511 1/20 0.34
HTT P42858 2/20 0.33
CHEK1 O14757 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PTPN22 Q9Y2R2 2/20 0.32
PTPRC P08575 1/20 0.32
PTPN9 P43378 1/20 0.32
PTPN11 Q06124 1/20 0.32
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2810745 0.79 ALOX15 (0.37) TDP1ALOX15ALDH1A1
SCHEMBL2710471 0.77 ALOX15 (0.35) TDP1ALOX15ALDH1A1KDM4ESMN1; SMN2
SCHEMBL2807400 0.77 TYMS (0.47) TDP1ALOX15ALDH1A1KDM4EMAPT
SCHEMBL29930656 0.77 ALOX15 (0.35) TDP1ALOX15ALDH1A1KDM4ESMN1; SMN2
SCHEMBL31415571 0.76 RARB (0.43) ALDH1A1KDM4ELMNAMAPTPTGS2
SCHEMBL28148705 0.76 ALOX15 (0.46) TDP1ALOX15CTRCHDAC4HDAC2
SCHEMBL31415561 0.75 TDP1 (0.38) TDP1HDAC4HDAC2HDAC8HDAC6
SCHEMBL542116 0.74 TDP1 (0.54) TDP1ALOX15CTRCHDAC4HDAC2
SCHEMBL2811395 0.73 KMT2A (0.42) TDP1ALOX15HDAC4HDAC2HDAC8
SCHEMBL30560809 0.73 TYMS (0.37) TDP1ALOX15ALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115818562-A Wet release process for silicon-based chip back cavity 苏州恒芯微电子有限公司 2023-03-21 CN claimed
CN-114891479-A Heat-resistant pressure-resistant rubber material and preparation method and application thereof 广东硕成科技股份有限公司 2022-08-12 CN claimed
US-7776434-B2 Organic matrix composite structures and thermal oxidative barrier coating therefor GENERAL ELECTRIC COMPANY (US) 2010-08-17 US claimed
US-20080146769-A1 RTM and RI Processible Tailorable Polyimide Resin Systems and Composite Articles Formed Therefrom GENERAL ELECTRIC COMPANY 2008-06-19 US claimed
WO-2024135665-A1 POLYIMIDE COMPOUND, NEGATIVE ELECTRODE MATERIAL FOR LITHIUM ION SECONDARY BATTERIES THAT USES SAID POLYIMIDE COMPOUND, NEGATIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERIES, AND LITHIUM ION SECONDARY BATTERY ウィンゴーテクノロジー株式会社 2024-06-27 WO disclosed
CN-114891479-A Heat-resistant pressure-resistant rubber material and preparation method and application thereof 广东硕成科技股份有限公司 2022-08-12 CN disclosed
EP-3708559-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS Rohm and Haas Electronic Materials LLC (US) 2020-09-16 EP disclosed
EP-3492444-B1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS ROHM & HAAS ELECT MAT (US) 2020-07-08 EP disclosed
US-20200087429-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVIED CURING KINETICS ROHM & HAAS ELECT MAT (US) 2020-03-19 US disclosed
US-20190169327-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-06-06 US disclosed
EP-3492444-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS Rohm and Haas Electronic Materials LLC (US) 2019-06-05 EP disclosed
WO-2019075786-A1 HIGH-TEMPERATURE-RESISTANT POLYIMIDE ADHESIVE FILM AND PREPARATION METHOD THEREFOR 黑龙江省科学院石油化学研究院 2019-04-25 WO disclosed
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP disclosed
EP-1586569-A1 Aryl ethynyl phthalic acid derivative and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-10-19 EP disclosed
US-20050215820-A1 Aryl ethynyl phthalic acid derivative and method for producing the same FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed
US-20040132900-A1 Polyimide compositions and use thereof in ceramic product defect repair INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-07-08 US disclosed
EP-1395627-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-10 EP disclosed
US-6653433-B2 From polyamic acids E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-25 US disclosed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO disclosed
US-20020010311-A1 From polyamic acids E.I. DU PONT DE NEMOURS AND COMPANY 2002-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087429-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVIED CURING KINETICS APEH, AADAC, KDM8 TDP1 930/4885ALOX15 331/4885CTRC 82/4885
US-20190169327-A1 METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS APEH, PAH, KDM8 TDP1 912/4885ALOX15 417/4885CTRC 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.