SCHEMBL29930656

SCHEMBL29930656

C#Cc1c(C)ccc2c1C(=O)OC2=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PAX8 Q06710 1/20 0.34
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
HBB P68871 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ELANE P08246 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710471 1.00 ALOX15 (0.35) ALOX15TDP1TDP2NSD2HSP90AA1
SCHEMBL2810745 0.80 ALOX15 (0.37) ALOX15TDP1ALDH1A1TYMS
SCHEMBL2807400 0.79 TYMS (0.47) ALOX15TDP1ALDH1A1TSHRKDM4E
SCHEMBL2811395 0.78 KMT2A (0.42) ALOX15TDP1HSP90AA1ALDH1A1CYP3A4
SCHEMBL1713019 0.77 TDP1 (0.39) ALOX15TDP1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL28740198 0.77 APP (0.38) ALOX15TDP1ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL1297841 0.75 TDP2 (0.56) ALOX15TDP1TDP2NSD2HSP90AA1
SCHEMBL29470951 0.75 TDP2 (0.56) ALOX15TDP1TDP2NSD2HSP90AA1
SCHEMBL28716021 0.74 ELANE (0.38) ELANE
SCHEMBL9617574 0.74 ALOX15 (0.30) ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114651031-B Reactive polyamideimide oligomers, methods, and articles 北卡罗来纳-查佩尔山大学 2025-02-25 CN claimed
CN-120059185-A Reactive polyamideimide oligomers, methods, and articles 北卡罗来纳-查佩尔山大学 2025-05-30 CN disclosed
CN-114651031-B Reactive polyamideimide oligomers, methods, and articles 北卡罗来纳-查佩尔山大学 2025-02-25 CN disclosed
WO-2025022386-A1 VITRIMERS, METHODS FOR THEIR PRODUCTION, AND USES THEREOF FOR COMPATIBILIZATION OF POLYMER BLENDS SHENKAR COLLEGE OF ENGINEERING AND DESIGN (IL) 2025-01-30 WO disclosed
EP-4055083-A1 REACTIVE POLYAMIDEIMIDE OLIGOMERS, METHODS, AND ARTICLES The University of North Carolina at Chapel Hill (US) 2022-09-14 EP disclosed
EP-4055084-A1 REACTIVE OLIGOMERS, ADDITIVE MANUFACTURING METHODS, AND ARTICLES THEREOF The University of North Carolina at Chapel Hill (US) 2022-09-14 EP disclosed