⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106841 | 0.90 | — | — | |
| SCHEMBL17106774 | 0.87 | — | — | |
| SCHEMBL17106691 | 0.86 | — | — | |
| SCHEMBL19412686 | 0.81 | SLC28A1 (0.32) | — | |
| SCHEMBL17106733 | 0.78 | STING1 (0.31) | — | |
| SCHEMBL17131357 | 0.75 | STING1 (0.30) | — | |
| SCHEMBL17106816 | 0.75 | POLRMT (0.34) | — | |
| SCHEMBL17106802 | 0.75 | POLRMT (0.34) | — | |
| SCHEMBL19412766 | 0.74 | SLC28A1 (0.32) | — | |
| SCHEMBL17106826 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015148746-A1 | 4'-SUBSTITUTED NUCLEOSIDE-DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-01 | — | — | WO | disclosed |