Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.31 |
| ▸ | GMPS | P49915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131357 | 0.87 | STING1 (0.30) | STING1 | |
| SCHEMBL19412686 | 0.87 | SLC28A1 (0.32) | SLC28A1SLC28A2STING1 | |
| SCHEMBL17106779 | 0.87 | SLC28A1 (0.30) | SLC28A1SLC28A2 | |
| SCHEMBL19412764 | 0.84 | STING1 (0.31) | SLC28A1SLC28A2STING1 | |
| SCHEMBL17106841 | 0.80 | — | — | |
| SCHEMBL17131355 | 0.79 | — | — | |
| SCHEMBL15259025 | 0.77 | STING1 (0.32) | ACVRL1STING1 | |
| SCHEMBL25401925 | 0.76 | POLRMT (0.37) | ACVRL1 | |
| SCHEMBL17131356 | 0.76 | STING1 (0.30) | STING1 | |
| SCHEMBL17106740 | 0.75 | ADRB1 (0.40) | SLC28A1SLC28A2STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |