SCHEMBL1713129

SCHEMBL1713129

COC(=O)C[S+]([O-])c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
TSHR P16473 2/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AKT1 P31749 1/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
APOBEC3A P31941 1/20 0.38
KMT2A Q03164 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPK1 P28482 2/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30828021 1.00 POLB (0.43) POLBTSHRKDM4EALDH1A1HSD17B10
SCHEMBL29182251 1.00 POLB (0.43) POLBTSHRKDM4EALDH1A1HSD17B10
SCHEMBL29182276 1.00 POLB (0.43) POLBTSHRKDM4EALDH1A1HSD17B10
SCHEMBL10961470 0.85 ALDH1A1 (0.44) POLBTSHRKDM4EALDH1A1HSD17B10
SCHEMBL30828001 0.84 TDP1 (0.41) POLBKDM4EALDH1A1HSD17B10LMNA
SCHEMBL6575536 0.82 PTGS2 (0.42) POLBALDH1A1HSD17B10SMN1; SMN2MEN1
SCHEMBL4908868 0.82 MEN1 (0.49) TSHRALDH1A1HSD17B10SMN1; SMN2MEN1
SCHEMBL29182262 0.82 HPGD (0.45) KDM4ELMNASMN1; SMN2MEN1KMT2A
SCHEMBL30828062 0.82 MEN1 (0.49) TSHRALDH1A1HSD17B10SMN1; SMN2MEN1
SCHEMBL17550689 0.82 GAA (0.38) TSHRKDM4EALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541830-A1 PROCESS FOR PRODUCING POLYURETHANE FOAM Covestro Deutschland AG (DE) 2025-04-23 EP claimed
EP-4541830-A1 PROCESS FOR PRODUCING POLYURETHANE FOAM Covestro Deutschland AG (DE) 2025-04-23 EP disclosed
EP-3976189-B1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES GALAPAGOS NV (BE) 2024-07-03 EP disclosed
CN-117802060-A Sulfoxide reductase mutant and application thereof in preparation of complex group chiral sulfoxide 遵义医科大学 2024-04-02 CN disclosed
CN-117778339-A Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester 遵义医科大学 2024-03-29 CN disclosed
US-11506670-B2 Method of genome-wide direct identification of electrophile-sensing targets CORNELL UNIVERSITY (US) 2022-11-22 US disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
WO-2020239658-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES GALAPAGOS NV (BE) 2020-12-03 WO disclosed
US-20190265250-A1 METHOD OF GENOME-WIDE DIRECT IDENTIFICATION OF ELECTROPHILE-SENSING TARGETS CORNELL UNIVERSITY 2019-08-29 US disclosed
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US disclosed
US-7157078-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-01-02 US disclosed
US-7030156-B2 Devices and methods for eliminating termite colonies UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC (US) 2006-04-18 US disclosed
US-20060054290-A1 Novel catalytic activities of oxidoreductases for oxidation and or bleaching CALL HANS-PETER 2006-03-16 US disclosed
WO-2006024611-A2 STABILIZATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-09 WO disclosed
US-6969512-B2 Devices and methods for eliminating termite colonies THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-29 US disclosed
US-6964124-B2 Devices and methods for eliminating termite colonies UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2005-11-15 US disclosed
US-6716421-B2 BAIT MATRICES AND BAIT STATIONS FOR ELIMINATING TERMITE COLONIES AND UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-04-06 US disclosed
EP-0194764-B1 PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1989-07-12 EP disclosed
EP-0194764-A1 Pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-09-17 EP disclosed