Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 7/20 | 0.58 |
| ▸ | CA1 | P00915 | 7/20 | 0.58 |
| ▸ | CA2 | P00918 | 7/20 | 0.58 |
| ▸ | CA9 | Q16790 | 7/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17107128 | 0.87 | RAB9A (0.71) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17107129 | 0.87 | RAB9A (0.71) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17132003 | 0.87 | RAB9A (0.71) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17107275 | 0.83 | ALOX5 (0.67) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17107273 | 0.83 | ALOX5 (0.67) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17131998 | 0.81 | RAB9A (0.53) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17133128 | 0.80 | RXFP1 (0.58) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL1427483 | 0.79 | SMN1; SMN2 (0.73) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL1427482 | 0.79 | SMN1; SMN2 (0.73) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17107111 | 0.77 | RAB9A (0.61) | RAB9ANPC1RECQLALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | XAVIER UNIVERSITY OF LOUISIANA | 2015-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274714-A1 | ANTI-MIGRATION AND ANTI-INVASION THIAZOLE ANALOGS FOR TREATMENT OF CELLULAR PROLIFERATIVE DISEASE | MKI67, MIF, NUDC | RAB9A 1305/4885NPC1 189/4885RECQL 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.