SCHEMBL1713367

SCHEMBL1713367

Clc1ccccc1C(SSC(c1ccccc1)(c1ccccc1)c1ccccc1Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.55
KIF11 P52732 7/20 0.51
TSHR P16473 4/20 0.42
KCNA3 P22001 2/20 0.42
CYP19A1 P11511 3/20 0.41
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
OPRK1 P41145 2/20 0.41
KCNH2 Q12809 2/20 0.41
LMNA P02545 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP1A2 P05177 2/20 0.41
ADRA1A P35348 1/20 0.41
MEN1 O00255 1/20 0.41
SLC22A1 O15245 1/20 0.41
NR1I2 O75469 1/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
TRPM2 O94759 1/20 0.41
ABCB11 O95342 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15053057 0.76 KIF11 (0.68) KIF11
SCHEMBL28502154 0.76 KCNN4 (0.57) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL7715769 0.75 KIF11 (0.48) KCNN4KIF11TSHRCYP1A2ALOX15
SCHEMBL8157067 0.75 KCNN4 (0.61) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL31364247 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL11654993 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL3239466 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL6337202 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL31364199 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1
SCHEMBL29354141 0.73 KCNN4 (0.59) KCNN4KIF11TSHRKCNA3CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-20160274084-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC 2016-09-22 US disclosed
US-9341576-B2 Detection of vapor phase compounds by changes in physical properties of a liquid crystal PLATYPUS TECHNOLOGIES, LLC (US) 2016-05-17 US disclosed
US-20160018371-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2016-01-21 US disclosed
WO-2014165196-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC (US) 2014-10-09 WO disclosed
US-20120288951-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2012-11-15 US disclosed
US-8178355-B2 Detection of vapor phase compounds by changes in physical properties of a liquid crystal PLATYPUS TECHNOLOGIES, LLC. (US) 2012-05-15 US disclosed
EP-2344879-A2 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL Platypus Technologies, LLC (US) 2011-07-20 EP disclosed
US-20100093096-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2010-04-15 US disclosed
WO-2010031047-A2 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2010-03-18 WO disclosed