SCHEMBL6337202

SCHEMBL6337202

Clc1ccccc1C(Cl)(Cl)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.59
TSHR P16473 8/20 0.52
KCNA3 P22001 2/20 0.44
CYP19A1 P11511 3/20 0.43
CYP3A4 P08684 3/20 0.43
HTR2A P28223 2/20 0.43
HTR2C P28335 2/20 0.43
OPRK1 P41145 2/20 0.43
KCNH2 Q12809 2/20 0.43
LMNA P02545 2/20 0.43
CYP1A2 P05177 2/20 0.43
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ADRA1A P35348 1/20 0.43
MEN1 O00255 1/20 0.43
SLC22A1 O15245 1/20 0.43
NR1I2 O75469 1/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
TRPM2 O94759 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4460056 0.86 CYP19A1 (0.49) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL4475144 0.85 TSHR (0.50) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL11724522 0.85 TSHR (0.55) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL8601255 0.85 KCNN4 (0.48) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL11860326 0.83 HSD11B1 (0.47) KCNN4TSHRCYP19A1HTR2AHTR2C
SCHEMBL11871226 0.83 KCNN4 (0.42) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL4470543 0.83 KCNN4 (0.42) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL4469654 0.83 CYP19A1 (0.53) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL11868546 0.81 KCNN4 (0.46) KCNN4TSHRKCNA3CYP19A1CYP3A4
SCHEMBL11654993 0.81 KCNN4 (0.59) KCNN4TSHRKCNA3CYP19A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105542053-A Polypeptide solid-phase synthesis matrix and preparation method thereof WUHAN NASEN BIOTECHNOLOGY CO LTD 2016-05-04 CN claimed
CN-117630242-A Method for separating and detecting impurity a in clotrimazole intermediate by high performance liquid chromatography 重庆华邦制药有限公司 2024-03-01 CN disclosed
CN-104277184-B A kind of preparation method of 2-chlorine trityl group chlorine resin SHENZHEN WEIQIU TECHNOLOGY CO., LTD. (CN) 2017-01-04 CN disclosed
CN-105542053-A Polypeptide solid-phase synthesis matrix and preparation method thereof WUHAN NASEN BIOTECHNOLOGY CO LTD 2016-05-04 CN disclosed
CN-103288591-B Method for preparing 1-chlorine-2-(dichloro(benzene)methyl) benzene solution NINGBO INST TECH ZHEJIANG UNIV 2015-02-18 CN disclosed
CN-103288591-B Method for preparing 1-chlorine-2-(dichloro(benzene)methyl) benzene solution NINGBO INST TECH ZHEJIANG UNIV 2015-02-18 CN disclosed
CN-103288591-B Method for preparing 1-chlorine-2-(dichloro(benzene)methyl) benzene solution NINGBO INST TECH ZHEJIANG UNIV 2015-02-18 CN disclosed
CN-104277184-A Preparation method of 2-trichlorophenylmethyl resin SHENZHEN WEIQIU TECHNOLOGY CO LTD 2015-01-14 CN disclosed
CN-103288591-A Method for preparing 1-chlorine-2-(dichloro(benzene)methyl) benzene solution NINGBO INST TECH ZHEJIANG UNIV 2013-09-11 CN disclosed
CN-103288591-A Method for preparing 1-chlorine-2-(dichloro(benzene)methyl) benzene solution NINGBO INST TECH ZHEJIANG UNIV 2013-09-11 CN disclosed
WO-2002042246-A1 METHOD FOR THE PREPARATION OF DICHLORODIARYLMETHANES TESSENDERLO CHEMIE N.V. (BE) 2002-05-30 WO disclosed
EP-1209147-A1 CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2002-05-29 EP disclosed
US-5326489-A Sulfonated polymer NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0445594-B1 An electrorheological fluid BRIDGESTONE CORP (JP) 1994-02-02 EP disclosed
EP-0523300-B1 Electrorheological fluids NIPPON CATALYTIC CHEM IND (JP) 1994-01-19 EP disclosed
US-5252250-A Increasing viscosity under application of electric potential difference BRIDGESTONE CORPORATION (JP) 1993-10-12 US disclosed
EP-0523300-A1 Electrorheological fluids NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1993-01-20 EP disclosed
EP-0445594-A1 An electrorheological fluid Bridgestone Corporation (JP) 1991-09-11 EP disclosed
US-4260506-A Hydraulic pressure device utilizing biodegradable halogenated diphenyl methanes MONSANTO COMPANY (US) 1981-04-07 US disclosed
US-3985766-A ANTIMYCOTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed