Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 17/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713673 | 0.99 | TSHR (0.49) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL1713630 | 0.99 | TSHR (0.51) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL18466633 | 0.94 | SLC5A2 (0.54) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL1713864 | 0.94 | SLC5A2 (0.54) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16882644 | 0.93 | SLC5A2 (0.48) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16882645 | 0.93 | SLC5A2 (0.48) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16871795 | 0.92 | SLC5A2 (0.60) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16871800 | 0.92 | SLC5A2 (0.60) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16871854 | 0.92 | SLC5A2 (0.60) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16882634 | 0.92 | SLC5A2 (0.60) | TSHRSLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881990-B1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INT (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-9127034-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivates and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9127034-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivates and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| EP-1989191-B1 | GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INT (DE) | 2011-07-20 | — | — | EP | disclosed |
| EP-1989191-B1 | GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INT (DE) | 2011-07-20 | — | — | EP | disclosed |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
| US-7772191-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-7772191-B2 | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-7745414-B2 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-29 | — | — | US | disclosed |
| US-7745414-B2 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-29 | — | — | US | disclosed |
| US-7745414-B2 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-29 | — | — | US | disclosed |
| EP-1989191-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | Boehringer Ingelheim International GmbH (DE) | 2008-11-12 | — | — | EP | disclosed |
| US-20080058379-A1 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058379-A1 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058379-A1 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| WO-2007093610-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007093610-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058379-A1 | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture | UGGT1, GALE, UGT1A4 | TSHR 3621/4885SLC5A2 4/4885SLC5A1 5/4885 |
| US-20100240879-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATES AND INTERMEDIATES THEREIN | UGGT1, B3GAT3, B4GALT1 | TSHR 3209/4885SLC5A2 123/4885SLC5A1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.