Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135859 | 1.00 | FAAH (0.44) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL16553285 | 1.00 | FAAH (0.44) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL16553284 | 1.00 | FAAH (0.44) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL16553283 | 1.00 | FAAH (0.44) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL17135858 | 1.00 | FAAH (0.44) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL13117260 | 0.91 | PTPN1 (0.37) | TDP1MAPTMAPK1 | |
| SCHEMBL19491098 | 0.86 | MEN1 (0.43) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL19490991 | 0.86 | MEN1 (0.43) | FAAHCNR2MEN1KMT2ATDP1 | |
| SCHEMBL31161063 | 0.81 | SLC6A4 (0.42) | MEN1KMT2AGAAKDM4EAPP | |
| SCHEMBL31161171 | 0.81 | SLC6A4 (0.42) | MEN1KMT2AGAAKDM4EAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795583-B2 | Composition for preventing or treating heart disease | AMOREPACIFIC CORPORATION (KR) | 2017-10-24 | — | — | US | disclosed |
| US-9795583-B2 | Composition for preventing or treating heart disease | AMOREPACIFIC CORPORATION (KR) | 2017-10-24 | — | — | US | disclosed |
| US-20150283110-A1 | COMPOSITION FOR PREVENTING OR TREATING HEART DISEASE | AMOREPACIFIC CORPORATION (KR) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283110-A1 | COMPOSITION FOR PREVENTING OR TREATING HEART DISEASE | SIRT1, SIRT3, SIRT2 | FAAH 3620/4885CNR2 3960/4885MEN1 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.