⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2259142 | 0.74 | — | — | |
| SCHEMBL21331725 | 0.74 | — | — | |
| SCHEMBL30987567 | 0.74 | HSD11B1 (0.37) | — | |
| SCHEMBL7759919 | 0.73 | — | — | |
| SCHEMBL10623983 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL27545401 | 0.72 | CYP3A4 (0.38) | — | |
| SCHEMBL8438478 | 0.69 | — | — | |
| SCHEMBL9763476 | 0.69 | CYP19A1 (0.30) | — | |
| SCHEMBL18683387 | 0.69 | — | — | |
| SCHEMBL4754696 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917190-B1 | NEW BENZENE SULFONAMIDE THIAZOLE COMPOUNDS | INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2017-07-19 | — | — | EP | disclosed |
| US-9567310-B2 | Benzene sulfonamide thiazole compounds | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHARCHE MEDICALE) (FR) | 2017-02-14 | — | — | US | disclosed |
| US-20150284347-A1 | NEW BENZENE SULFONAMIDE THIAZOLE COMPOUNDS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2015-10-08 | — | — | US | disclosed |