⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15399539 | 0.78 | — | — | |
| SCHEMBL4754696 | 0.78 | — | — | |
| SCHEMBL23357784 | 0.78 | — | — | |
| SCHEMBL8813249 | 0.78 | — | — | |
| SCHEMBL10626473 | 0.74 | — | — | |
| SCHEMBL17136152 | 0.73 | — | — | |
| SCHEMBL9711596 | 0.70 | — | — | |
| SCHEMBL9763476 | 0.70 | CYP19A1 (0.30) | — | |
| SCHEMBL7918141 | 0.70 | — | — | |
| SCHEMBL4953742 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162802-B1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | NIHON MEDIPHYSICS CO LTD (JP) | 2020-08-19 | — | — | EP | disclosed |
| CN-106458995-B | 2- (3-pyridyl) -1H-benzimidazole derivative compound and medicine containing the same | 日本医事物理股份有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-10358434-B2 | 2-(3-pyridinyl)-1H-benzimidazole derivative compound and medicament containing same | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2019-07-23 | — | — | US | disclosed |
| US-20190169169-A1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICAMENT CONTAINING SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-10189815-B2 | 2-(3-pyridinyl)-1H-benzimidazole derivative compound and medicine containing same | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20170158668-A1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2017-06-08 | — | — | US | disclosed |
| EP-3162802-A1 | 2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
| EP-0721441-B1 | HALOGENATION REACTIONS | F2 CHEMICALS LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| US-5734073-A | Halogenation reactions | BNFL FLUOROCHEMICALS LTD (GB) | 1998-03-31 | — | — | US | disclosed |