SCHEMBL171365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5227679	0.83	HDAC1 (0.55)	HDAC4KCNH2
	SCHEMBL169482	0.82	DRD4 (0.52)	OPRM1OPRK1HDAC4DRD4DRD3
	SCHEMBL105201	0.81	DRD4 (0.53)	OPRM1OPRK1DRD4DRD3DRD2
	SCHEMBL13490533	0.80	GRM5 (0.50)	MEN1KMT2ANAMPTGAA
	SCHEMBL171316	0.80	DRD4 (0.53)	HDAC4DRD4DRD3DRD2NAMPT
	SCHEMBL171672	0.80	DRD4 (0.52)	OPRM1OPRK1HDAC4DRD4DRD3
	SCHEMBL14544155	0.79	NAMPT (0.53)	DRD4DRD3DRD2MEN1KMT2A
	SCHEMBL13490436	0.79	DRD4 (0.52)	HDAC4DRD4DRD3DRD2NAMPT
	SCHEMBL13490527	0.77	SIGMAR1 (0.54)	OPRM1OPRK1HDAC4DRD4DRD3
	SCHEMBL171676	0.77	DRD4 (0.49)	OPRM1OPRK1DRD4DRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.