Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.49 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544153 | 0.89 | NAMPT (0.52) | NAMPTWNT3AGRM5LNPEPBTK | |
| SCHEMBL171543 | 0.85 | GRIN2B (0.42) | NAMPTCYP3A4CYP2D6CYP2C9GRIN2B | |
| SCHEMBL13490526 | 0.84 | GRM5 (0.53) | NAMPTWNT3AGRM5LNPEPBTK | |
| SCHEMBL30899650 | 0.81 | GRM5 (0.52) | NAMPTGRM5LNPEPBTKPRMT1 | |
| SCHEMBL30365847 | 0.81 | GRM5 (0.52) | NAMPTGRM5LNPEPBTKPRMT1 | |
| SCHEMBL13490532 | 0.81 | GRM5 (0.52) | NAMPTWNT3AGRM5LNPEPBTK | |
| SCHEMBL1577496 | 0.81 | GRM5 (0.52) | NAMPTWNT3AGRM5LNPEPBTK | |
| SCHEMBL171369 | 0.81 | GRM5 (0.52) | NAMPTWNT3AGRM5LNPEPBTK | |
| SCHEMBL171485 | 0.81 | GRM5 (0.52) | NAMPTGRM5LNPEPBTKPRMT1 | |
| SCHEMBL13490533 | 0.80 | GRM5 (0.50) | NAMPTGRM5LNPEPBTKPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |