Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538876 | 0.91 | ALDH1A1 (0.49) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL31009671 | 0.91 | ALDH1A1 (0.72) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL660365 | 0.91 | ALDH1A1 (0.72) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL1159006 | 0.91 | ALDH1A1 (0.72) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL1121408 | 0.86 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3TSHRFDPSHPGD | |
| SCHEMBL20710995 | 0.86 | ALDH1A1 (0.47) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL12476044 | 0.85 | ALDH1A3 (0.53) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL28965218 | 0.85 | ALDH1A3 (0.53) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL3431679 | 0.85 | ALDH1A3 (0.53) | ALDH1A1ALDH1A3TSHRFDPSAOX1 | |
| SCHEMBL20529376 | 0.83 | ALDH1A3 (0.52) | ALDH1A1ALDH1A3TSHRFDPSAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466795-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2025-11-11 | — | — | US | disclosed |
| US-20240150288-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2024-05-09 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| EP-4023294-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Cognition Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-4023294-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Cognition Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3498692-B1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE AND MACULAR DEGENERATION | COGNITION THERAPEUTICS INC (US) | 2022-03-16 | — | — | EP | disclosed |
| US-20210009517-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2021-01-14 | — | — | US | disclosed |
| US-10611728-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| US-10611728-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| US-4897418-A | ANTILIPEMIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| CN-1006464-B | PROCESS FOR PREPARING NAPHTHALENE DERIVATIVES | TANABE SEIYAKU CO (JP) | 1990-01-17 | — | — | CN | disclosed |
| US-4771072-A | HYPOLIPIDEMIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| CN-86100090-A | The preparation method of naphthalene derivatives | — | 1986-08-20 | — | — | CN | disclosed |
| EP-0188248-A2 | Naphthalene derivatives, process for the preparation thereof and pharmaceutical composition containing same | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4491583-A | HETEROCYCLIC UREA COMPOUNDS | PFIZER INC. (US) | 1985-01-01 | — | — | US | disclosed |
| US-4258061-A | TO COMBAT VIRAL DISEASE | PFIZER INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4087552-A | ANTIVIRAL | PFIZER INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4034040-A | Xylene-diamines as antiviral agents | PFIZER INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-4000130-A | INDOLE DYES, POLYACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH1A3 3604/4885TSHR 4018/4885 |
| US-20240150288-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH1A3 3604/4885TSHR 4018/4885 |
| US-12466795-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH1A3 3604/4885TSHR 4018/4885 |
| US-10611728-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH1A3 3604/4885TSHR 4018/4885 |
| US-20210009517-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, PSD | ALDH1A1 4160/4885ALDH1A3 3604/4885TSHR 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.