Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713448 | 0.93 | HTT (0.75) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL11872109 | 0.90 | MAPT (0.76) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL1713392 | 0.83 | FEN1 (0.60) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL12462461 | 0.82 | HTT (0.47) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL7019413 | 0.80 | FEN1 (0.50) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL7019417 | 0.80 | FEN1 (0.50) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL4316407 | 0.79 | FEN1 (0.60) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL7014430 | 0.78 | MAPT (0.48) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL7014427 | 0.78 | MAPT (0.48) | HTTMAPTFEN1CYP1A2CYP2C9 | |
| SCHEMBL1713792 | 0.78 | FEN1 (0.66) | HTTMAPTFEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| EP-1985445-B1 | A lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2011-07-20 | — | — | EP | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| WO-2008132091-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1985445-A1 | A lithographic printing plate precursor | Agfa Graphics N.V. (BE) | 2008-10-29 | — | — | EP | disclosed |