Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872109 | 0.95 | MAPT (0.76) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL1713804 | 0.93 | HTT (0.64) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL1713392 | 0.83 | FEN1 (0.60) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL12462461 | 0.77 | HTT (0.47) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL8652560 | 0.76 | MPO (0.72) | MAPTKDM4EALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL1713792 | 0.75 | FEN1 (0.66) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL7014427 | 0.75 | MAPT (0.48) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL7014430 | 0.75 | MAPT (0.48) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL7019413 | 0.74 | FEN1 (0.50) | HTTMAPTKDM4EALDH1A1NSD2 | |
| SCHEMBL7019417 | 0.74 | FEN1 (0.50) | HTTMAPTKDM4EALDH1A1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| US-8192918-B2 | Lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-06-05 | — | — | US | disclosed |
| EP-1985445-B1 | A lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2011-07-20 | — | — | EP | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| US-20100112476-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2010-05-06 | — | — | US | disclosed |
| EP-1985445-A1 | A lithographic printing plate precursor | Agfa Graphics N.V. (BE) | 2008-10-29 | — | — | EP | disclosed |