Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138099 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL17138106 | 0.80 | KCNH2 (0.34) | KCNH2GCGR | |
| SCHEMBL17138107 | 0.64 | ELANE (0.35) | KCNH2 | |
| SCHEMBL28093226 | 0.64 | KCNH2 (0.34) | KCNH2GCGR | |
| SCHEMBL26617307 | 0.64 | GCGR (0.36) | KCNH2GCGR | |
| SCHEMBL862297 | 0.63 | GCGR (0.50) | KCNH2GCGR | |
| SCHEMBL13589745 | 0.62 | KCNH2 (0.38) | KCNH2GCGR | |
| SCHEMBL17694341 | 0.62 | KDM4E (0.43) | — | |
| SCHEMBL2713322 | 0.62 | MEN1 (0.33) | — | |
| SCHEMBL28092990 | 0.62 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-08 | — | — | US | claimed |
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | DHPS, COASY, CDK18 | KCNH2 1241/4885GCGR 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.