Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 8/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176727 | 0.86 | RAB9A (0.42) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL17694344 | 0.86 | RARB (0.38) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL20176717 | 0.85 | KDM4E (0.41) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL16546613 | 0.84 | KDM4E (0.40) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL20176724 | 0.84 | KDM4E (0.40) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL20176733 | 0.82 | KDM4E (0.39) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL18665481 | 0.81 | PTGS2 (0.30) | KDM4EHSD17B10ALDH1A1RARBRARA | |
| SCHEMBL20176736 | 0.79 | ALOX15B (0.38) | KDM4ERAB9AHSD11B1PTPN1EIF4A1 | |
| SCHEMBL2466020 | 0.79 | HSD17B10 (0.55) | KDM4ERAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL6418801 | 0.79 | HSD17B10 (0.55) | KDM4ERAB9AHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029702-A1 | LIQUID CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | MERCK PATENT GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | CRY1, SLC25A1, CRY2 | KDM4E 2034/4885RAB9A 1322/4885HSD17B10 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.