Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14795390 | 0.91 | CYP1A2 (0.42) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL14895353 | 0.89 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL29686646 | 0.86 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL9253450 | 0.84 | CA1 (0.30) | CHRNB2CHRNA7CHRNA4CA1CA2 | |
| SCHEMBL9232926 | 0.84 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL10424059 | 0.83 | CHRNB2 (0.34) | CHRNB2CHRNA7CHRNA4EPHX1SIGMAR1 | |
| SCHEMBL28683282 | 0.82 | CHRNB2 (0.45) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL8675580 | 0.82 | CYP1A2 (0.52) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL29904850 | 0.80 | EPHX1 (0.48) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 | |
| SCHEMBL29455101 | 0.80 | EPHX1 (0.48) | CHRNB2CHRNA7CHRNA4CYP1A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284504-A1 | HETEROCYCLIC COMPOUNDS AND THE SYNTHESIS METHOD THEREOF | DHPS, COASY, CDK18 | CHRNB2 4307/4885CHRNA7 4601/4885CHRNA4 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.