SCHEMBL1714045

SCHEMBL1714045

COc1ccnc2c(O)cccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
MAPT P10636 5/20 0.54
ALOX12 P18054 3/20 0.54
LMNA P02545 2/20 0.54
TP53 P04637 2/20 0.54
TSHR P16473 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.51
RAB9A P51151 2/20 0.51
KDM4A O75164 1/20 0.51
EGLN1 Q9GZT9 1/20 0.51
HIF1AN Q9NWT6 1/20 0.51
NPC1 O15118 2/20 0.51
MEN1 O00255 2/20 0.51
HSP90AA1 P07900 2/20 0.51
KMT2A Q03164 2/20 0.51
NSD2 O96028 1/20 0.51
CASP6 P55212 1/20 0.51
SLC40A1 Q9NP59 1/20 0.49
HTT P42858 3/20 0.47
ADRA1A P35348 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4294109 0.98 KDM4E (0.53) KDM4EMAPTALOX12LMNATP53
SCHEMBL2224753 0.86 HSP90AA1 (0.62) KDM4EMAPTALOX12LMNAL3MBTL1
SCHEMBL12530859 0.83 KDM4E (0.56) KDM4EMAPTALOX12LMNATP53
SCHEMBL22413940 0.82 KDM4E (0.41) KDM4EMAPTALOX12LMNATP53
SCHEMBL18594969 0.82 KDM4E (0.41) KDM4EMAPTALOX12LMNATP53
SCHEMBL14871760 0.80 HTR1A (0.53) SLC40A1ADRA1AHTR1AADRA1DADRA1B
SCHEMBL13621091 0.80 SLC40A1 (0.42) KDM4EMAPTTP53TSHRNPC1
SCHEMBL8277995 0.80 HTR1A (0.53) SLC40A1ADRA1AHTR1AADRA1DADRA1B
SCHEMBL7247375 0.79 NSD2 (0.54) MAPTMEN1KMT2ANSD2CASP6
SCHEMBL2699726 0.79 HTR1A (0.59) KDM4EMAPTALOX12LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071478-A Compound for targeted degradation of GLI1 protein and medicinal application thereof 苏州大学 2026-05-22 CN disclosed
WO-2014061647-A1 PRENYLOXYQUINOLINE CARBOXYLIC-ACID DERIVATIVE 公立大学法人福島県立医科大学 (JP) 2014-04-24 WO disclosed
EP-1755362-B1 ORGANIC EL DEVICE TOYOTA JIDOSHOKKI KK (JP) 2011-07-20 EP disclosed
WO-2011077226-A1 PROCEDURE FOR THE SYNTHESIS OF FLUORESCENT PROBES FOR METALS ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) 2011-06-30 WO disclosed
US-7854998-B2 Organic EL devices KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2010-12-21 US disclosed
US-20080290788-A1 Organic el Devices KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2008-11-27 US disclosed
EP-1755362-A1 ORGANIC EL DEVICE KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2007-02-21 EP disclosed
US-20070018568-A1 Organic electroluminescent device KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2007-01-25 US disclosed
US-20060228577-A1 Organic electroluminescent device KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2006-10-12 US disclosed
EP-1599074-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kabushiki Kaisha Toyota Jidoshokki (JP) 2005-11-23 EP disclosed
EP-1560469-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kabushiki Kaisha Toyota Jidoshokki (JP) 2005-08-03 EP disclosed