Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400639 | 0.83 | ESR1 (0.51) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL3174968 | 0.82 | MEN1 (0.44) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL27675385 | 0.80 | ESR1 (0.54) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL561439 | 0.80 | KLF10 (0.66) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL17141707 | 0.80 | FFAR4 (0.53) | FFAR4 | |
| SCHEMBL23886964 | 0.79 | MEN1 (0.46) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL14131082 | 0.79 | FFAR4 (0.43) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL178283 | 0.78 | ESR1 (0.69) | MEN1KMT2AFFAR4ESR1ESR2 | |
| SCHEMBL18586260 | 0.77 | IDO1 (0.39) | CYP2D6IDO1TAAR1CYP3A4 | |
| SCHEMBL8390910 | 0.76 | CYP2D6 (0.60) | MEN1KMT2AESR1ESR2KLF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137415-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2017-05-18 | — | — | US | disclosed |
| EP-3126360-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | Lupin Limited (IN) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015151001-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137415-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | SCN7A, SCN1A, SCN5A | MEN1 3401/4885KMT2A 1447/4885FFAR4 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.