Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141753 | 0.92 | HTR2C (0.53) | RXRARXRBRXRGHTR2CSLC6A4 | |
| SCHEMBL17141510 | 0.83 | RXRA (0.53) | FFAR4PTPN1PTPN6PTPN2RXRA | |
| SCHEMBL6216861 | 0.80 | HTR2C (0.54) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL6211474 | 0.80 | RXRA (0.55) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL538233 | 0.80 | RXRA (0.57) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL17141554 | 0.80 | MEN1 (0.47) | FFAR4 | |
| SCHEMBL4720380 | 0.80 | RXRA (0.65) | FFAR4PTPN1PTPN6PTPN2RXRA | |
| SCHEMBL17141539 | 0.78 | HTR2C (0.54) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL561476 | 0.78 | HTR2C (0.54) | PTPN1PTPN6PTPN2RXRARXRB | |
| SCHEMBL4723962 | 0.76 | RXRA (0.57) | PTPN1PTPN6PTPN2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126360-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | Lupin Limited (IN) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015151001-A1 | SULFONAMIDE COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2015-10-08 | — | — | WO | disclosed |