SCHEMBL17142007

SCHEMBL17142007

CC1(C)OB(c2cc3ccccc3cc2-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-3)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.40
LIPG Q9Y5X9 2/20 0.40
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
PDK2 Q15119 2/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21257259 0.89 LPL (0.47) LPLLIPGKDM4EMEN1LMNA
SCHEMBL18421040 0.88 LPL (0.40) LPLLIPGKDM4EMEN1LMNA
SCHEMBL17142015 0.85 LPL (0.44) LPLLIPGPDK2DGAT1
SCHEMBL21524336 0.82 LPL (0.38) LPLLIPGKDM4EMEN1LMNA
SCHEMBL17142019 0.82 LPL (0.39) LPLLIPGKDM4EMEN1LMNA
SCHEMBL31050382 0.82 LPL (0.39) LPLLIPG
SCHEMBL24257896 0.81 LIPG (0.57) LPLLIPGKDM4EMEN1LMNA
SCHEMBL17143472 0.81 LIPG (0.57) LPLLIPGKDM4EMEN1LMNA
SCHEMBL17143469 0.81 LIPG (0.57) LPLLIPGKDM4EMEN1LMNA
SCHEMBL24287222 0.79 LPL (0.33) LPLLIPGESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106164055-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2019-12-27 CN disclosed
WO-2015152651-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2015-10-08 WO disclosed