Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080142 | 0.74 | CHEK2 (0.41) | — | |
| SCHEMBL17142684 | 0.70 | PARP1 (0.39) | PARP1PARP2 | |
| SCHEMBL17144869 | 0.68 | LMNA (0.38) | — | |
| SCHEMBL31707018 | 0.64 | — | — | |
| SCHEMBL13729857 | 0.63 | PARP1 (0.40) | PARP1PARP2 | |
| SCHEMBL6806620 | 0.61 | HRH1 (0.39) | — | |
| SCHEMBL6802422 | 0.61 | HRH1 (0.44) | — | |
| SCHEMBL17144873 | 0.58 | LMNA (0.38) | — | |
| SCHEMBL13908766 | 0.56 | CYP3A4 (0.41) | — | |
| SCHEMBL8927501 | 0.56 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126337-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |