Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720416 | 0.81 | PARP1 (0.40) | PARP1PARP2 | |
| SCHEMBL22720412 | 0.68 | PARP1 (0.42) | PARP1PARP2 | |
| SCHEMBL17142684 | 0.68 | PARP1 (0.39) | PARP1PARP2 | |
| SCHEMBL28227905 | 0.65 | PARP1 (0.55) | PARP1PARP2 | |
| SCHEMBL28569805 | 0.65 | — | — | |
| SCHEMBL6644584 | 0.65 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL10002467 | 0.65 | ALDH1A1 (0.50) | — | |
| SCHEMBL30751437 | 0.64 | PARP1 (0.51) | PARP1PARP2 | |
| Acetic Acid SCHEMBL27199873 | 0.64 | GRM5 (0.44) | — | |
| SCHEMBL27968289 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |