Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15640068 | 0.75 | PTGES (0.44) | GAALMNAALDH1A1TP53 | |
| SCHEMBL17064210 | 0.71 | PTGES (0.41) | GAALMNATP53 | |
| SCHEMBL16463188 | 0.67 | HTT (0.55) | GAAMCOLN3NPSR1POLBGPBAR1 | |
| SCHEMBL15639435 | 0.65 | PTGES (0.44) | GAALMNATP53 | |
| SCHEMBL4469871 | 0.64 | TSHR (0.50) | GAALMNAALDH1A1TP53CTNNB1 | |
| SCHEMBL29571767 | 0.63 | PTGES (0.41) | GAALMNATP53 | |
| SCHEMBL15638844 | 0.63 | PTGES (0.41) | GAALMNATP53 | |
| SCHEMBL16463131 | 0.61 | CYP3A4 (0.46) | GPBAR1TP53 | |
| SCHEMBL16465413 | 0.61 | KCNA5 (0.40) | GAANPSR1LMNAGPBAR1TP53 | |
| SCHEMBL1379219 | 0.60 | TSHR (0.46) | NPSR1LMNAGPBAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3125692-B1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AG (DE) | 2021-01-27 | — | — | EP | disclosed |
| EP-3125692-B1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AG (DE) | 2021-01-27 | — | — | EP | disclosed |
| US-10258038-B2 | Use of heterocyclic compounds for controlling nematodes | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-16 | — | — | US | disclosed |
| US-10258038-B2 | Use of heterocyclic compounds for controlling nematodes | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-16 | — | — | US | disclosed |
| US-20170135346-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170135346-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170135346-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| EP-3125692-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| WO-2015150252-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
| WO-2015150252-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170135346-A1 | USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES | DDT, CYCS, CYC1 | GRIN2B 4227/4885CACNA2D1 3880/4885GRIN1 3954/4885 |
| US-10258038-B2 | Use of heterocyclic compounds for controlling nematodes | DDT, CYCS, CYC1 | GRIN2B 4227/4885CACNA2D1 3880/4885GRIN1 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.