Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PCNA | P12004 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309409 | 0.84 | SMN1; SMN2 (0.44) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10304153 | 0.83 | MEN1 (0.56) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL14546558 | 0.82 | EPHX2 (0.57) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13073508 | 0.81 | SMN1; SMN2 (0.42) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23677003 | 0.81 | ALDH1A1 (0.47) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13687327 | 0.81 | ALDH1A1 (0.48) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9735108 | 0.81 | EPHX2 (0.44) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL18199506 | 0.79 | MEN1 (0.52) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12107521 | 0.79 | CASP2 (0.53) | EPHX2SMN1; SMN2TSHRPCNAHPGD | |
| SCHEMBL459746 | 0.79 | EPHX2 (0.42) | EPHX2RAB9AALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160114052-A1 | POTENT CONJUGATES AND HYDROPHILIC LINKERS | IMMUNOGEN, INC. (US) | 2016-04-28 | — | — | US | disclosed |
| US-9150649-B2 | Potent conjugates and hydrophilic linkers | IMMUNOGEN, INC. (US) | 2015-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114052-A1 | POTENT CONJUGATES AND HYDROPHILIC LINKERS | CD44, EPCAM, ABCG2 | EPHX2 859/4885RAB9A 4063/4885ALDH1A1 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.