SCHEMBL171454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13592728	0.84	PDE2A (0.46)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL13490427	0.76	CYP2D6 (0.48)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL171346	0.72	CYP3A4 (0.49)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL13490665	0.70	CYP3A4 (0.50)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL171619	0.70	PDE2A (0.55)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL13490502	0.70	PDE2A (0.49)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL13490597	0.69	HRH2 (0.56)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL30223604	0.69	PDE2A (0.42)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL17898213	0.69	CYP3A4 (0.53)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19
	SCHEMBL13490514	0.68	CYP3A4 (0.58)	CYP3A4CYP2D6CYP1A2ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.