Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145730 | 0.83 | CYP19A1 (0.44) | CYP19A1TLR9MAPTALDH1A1MEN1 | |
| SCHEMBL17145740 | 0.82 | TUBB4A (0.54) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17145739 | 0.82 | CYP1A1 (0.60) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL5071908 | 0.81 | CYP1A2 (0.66) | CYP19A1TLR9MAPTALDH1A1MEN1 | |
| SCHEMBL5071907 | 0.81 | CYP1A2 (0.66) | CYP19A1TLR9MAPTALDH1A1MEN1 | |
| SCHEMBL17145769 | 0.81 | TUBB4A (0.64) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2980561 | 0.78 | CYP19A1 (0.74) | CYP19A1TLR9MAPTALDH1A1MEN1 | |
| SCHEMBL2980565 | 0.78 | CYP19A1 (0.74) | CYP19A1TLR9MAPTALDH1A1MEN1 | |
| SCHEMBL17145768 | 0.78 | CYP1A2 (0.49) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10030782 | 0.77 | TUBB1 (0.56) | CYP19A1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45907-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-RE45720-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2015-10-06 | — | — | US | disclosed |