Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980565 | 1.00 | CYP19A1 (0.74) | CYP19A1PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL14046248 | 0.92 | CYP19A1 (0.64) | CYP19A1PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL227065 | 0.90 | TLR9 (0.60) | CYP19A1PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL227066 | 0.90 | TLR9 (0.60) | CYP19A1PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL5071907 | 0.86 | CYP1A2 (0.66) | CYP19A1PTGS2CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL5071908 | 0.86 | CYP1A2 (0.66) | CYP19A1PTGS2CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL11745232 | 0.84 | CYP19A1 (0.72) | CYP19A1CYP1A2CYP1A1CYP1B1MAPT | |
| SCHEMBL11745227 | 0.84 | CYP19A1 (0.72) | CYP19A1CYP1A2CYP1A1CYP1B1MAPT | |
| SCHEMBL15938082 | 0.83 | CYP19A1 (0.51) | CYP19A1CYP1A2CYP1A1CYP1B1MAPT | |
| SCHEMBL15938083 | 0.83 | CYP19A1 (0.51) | CYP19A1CYP1A2CYP1A1CYP1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781580-B2 | Stilbene derivatives as new cancer therapeutic agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2010-08-24 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261982-A1 | STILBENE DERIVATIVES AS NEW CANCER THERAPEUTIC AGENTS | HDGF, TIE1, VEGFA | CYP19A1 2015/4885PTGS2 252/4885PTGS1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.