SCHEMBL17146191

SCHEMBL17146191

CC(=O)NOCc1c(F)cccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.44
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
MTNR1A P48039 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 1/20 0.36
PTPN1 P18031 1/20 0.36
ERCC5 P28715 1/20 0.36
FEN1 P39748 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15761156 0.88 ALDH1A1 (0.44) ALDH1A1KDM4ELMNAMTNR1ASMN1; SMN2
SCHEMBL15761293 0.86 ALB (0.41) ALBALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL19229829 0.84 KDM4E (0.46) ALDH1A1KDM4ELMNAMTNR1ANPC1
SCHEMBL19229830 0.82 TSHR (0.45) ALDH1A1KDM4ELMNAMTNR1ANPC1
SCHEMBL17146200 0.82 MTNR1A (0.39) ALDH1A1KDM4EMTNR1ASMN1; SMN2NPC1
SCHEMBL17146204 0.82 CLCN2 (0.46) ALDH1A1KDM4EMTNR1ANPC1RAB9A
SCHEMBL19229480 0.82 ALDH1A1 (0.43) ALDH1A1KDM4ELMNAMTNR1ASMN1; SMN2
SCHEMBL15761301 0.82 KDM4E (0.37) ALDH1A1KDM4EMTNR1ASMN1; SMN2GAA
SCHEMBL20342810 0.80 ALDH1A1 (0.35) ALDH1A1KDM4ELMNAMTNR1ASMN1; SMN2
SCHEMBL16892196 0.80 ALB (0.50) ALBALDH1A1KDM4ESMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
EP-2927218-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-07 EP disclosed