SCHEMBL1714740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1715384	0.88	KDR (0.52)	ALDH1A1KDM4EHPGDHSD17B10POLB
	SCHEMBL1715363	0.83	KDM4C (0.64)	KDM4EKDM6BKDM4AKDM4DKDM4C
	SCHEMBL1715783	0.83	KMT2A (0.47)	USP2KMT2AALDH1A1MEN1ALOX15
	SCHEMBL1715877	0.82	PTGS2 (0.54)	KDM4EGAAKDM6BKDM4AKDM4D
	SCHEMBL1715462	0.81	PTGS2 (0.46)	KMT2AALDH1A1MEN1ALOX15KDM4E
	SCHEMBL1715256	0.81	KDM4C (0.54)	ALDH1A1KDM4EHPGDHSD17B10POLB
	SCHEMBL1715406	0.81	KDR (0.53)	ALDH1A1KDM4EHPGDHSD17B10POLB
	SCHEMBL1715301	0.81	NPC1 (0.50)	KMT2AMEN1TSHRNPC1RAB9A
	SCHEMBL1715827	0.81	NPC1 (0.48)	KMT2AALDH1A1ALOX15KDM4EHPGD
	SCHEMBL1715108	0.81	L3MBTL1 (0.54)	KMT2AALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.