Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148246 | 0.77 | KMT2A (0.52) | CYP1A2CYP2D6CYP2C9MEN1KMT2A | |
| SCHEMBL20205224 | 0.76 | HTT (0.50) | CYP1A2CYP2D6L3MBTL1MEN1KMT2A | |
| SCHEMBL17142511 | 0.74 | KMT2A (0.54) | CYP1A2CYP2D6CYP2C9KMT2APOLB | |
| SCHEMBL17142958 | 0.73 | CHRNA7 (0.51) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17143130 | 0.73 | KMT2A (0.55) | KMT2APOLBALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL19840606 | 0.73 | EPHX2 (0.49) | L3MBTL1KMT2AKDM4E | |
| SCHEMBL17148153 | 0.73 | EPHX2 (0.49) | L3MBTL1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL17148175 | 0.73 | EPHX2 (0.45) | CYP1A2CYP2D6CYP2C9KMT2AALDH1A1 | |
| SCHEMBL17142843 | 0.72 | CHRNA7 (0.49) | L3MBTL1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7127675 | 0.72 | CYP1A2 (0.45) | NPSR1CYP1A2CYP2D6CYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |