Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148282 | 0.89 | EPHX2 (0.46) | EPHX2KMT2ACNR1EGFRLMNA | |
| SCHEMBL17148153 | 0.88 | EPHX2 (0.49) | EPHX2KMT2ACNR1LMNAGAA | |
| SCHEMBL17142872 | 0.84 | EPHX2 (0.47) | EPHX2KMT2ACNR1LMNAMAPT | |
| SCHEMBL17148246 | 0.84 | KMT2A (0.52) | EPHX2KMT2ALMNAATR | |
| SCHEMBL17142435 | 0.83 | EPHX2 (0.48) | EPHX2KMT2ACNR1LMNAMAPT | |
| SCHEMBL17148295 | 0.83 | EPHX2 (0.47) | EPHX2EGFRLMNACDK1CCNB1 | |
| SCHEMBL19840635 | 0.82 | EPHX2 (0.45) | EPHX2KMT2ACNR1LMNAMAPT | |
| SCHEMBL17148308 | 0.82 | KMT2A (0.48) | EPHX2KMT2ACNR1LMNAMAPT | |
| SCHEMBL19840603 | 0.81 | EPHX2 (0.45) | EPHX2KMT2ALMNACDK1CCNB1 | |
| SCHEMBL18396142 | 0.81 | HTR3A (0.46) | EPHX2KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |