Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148246 | 0.93 | KMT2A (0.52) | EPHX2KMT2ANAMPTKCNH2CHRNA7 | |
| SCHEMBL17142511 | 0.89 | KMT2A (0.54) | EPHX2KMT2ANAMPTKCNH2CHRNA7 | |
| SCHEMBL17143130 | 0.88 | KMT2A (0.55) | EPHX2KITKMT2ANAMPTKCNH2 | |
| SCHEMBL19840635 | 0.87 | EPHX2 (0.45) | EPHX2KITKMT2AKCNH2LMNA | |
| SCHEMBL17148171 | 0.86 | CDK1 (0.45) | EPHX2KITKMT2ANAMPTKCNH2 | |
| SCHEMBL17148201 | 0.86 | KMT2A (0.55) | EPHX2KMT2ANAMPTKCNH2CHRNA7 | |
| SCHEMBL17148296 | 0.85 | KIT (0.46) | EPHX2KITKMT2AKCNH2CHRNA7 | |
| SCHEMBL19840602 | 0.84 | SMN1; SMN2 (0.48) | EPHX2KITKMT2AKCNH2CHRNA7 | |
| SCHEMBL17142408 | 0.83 | HTR3A (0.55) | EPHX2KMT2ANAMPTKCNH2CHRNA7 | |
| SCHEMBL17148299 | 0.83 | KMT2A (0.47) | KMT2ALMNAALDH1A1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |