Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148171 | 0.92 | CDK1 (0.45) | KITSMN1; SMN2KMT2ACDK1CCNB1 | |
| SCHEMBL17148246 | 0.90 | KMT2A (0.52) | SMN1; SMN2KMT2ARAB9AMAPK1HTT | |
| SCHEMBL17148299 | 0.90 | KMT2A (0.47) | SMN1; SMN2KMT2ACDK1CCNB1CCNA2 | |
| SCHEMBL17148279 | 0.88 | EPHX2 (0.44) | KITKMT2ACDK1CCNB1CCNA2 | |
| SCHEMBL17142511 | 0.86 | KMT2A (0.54) | SMN1; SMN2KMT2ARAB9AMAPK1HTT | |
| SCHEMBL17143130 | 0.85 | KMT2A (0.55) | KITSMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL17148175 | 0.85 | EPHX2 (0.45) | KITSMN1; SMN2KMT2AMCHR1HTR2C | |
| SCHEMBL17148343 | 0.84 | TP53 (0.49) | KITSMN1; SMN2KMT2AMAPTHTT | |
| SCHEMBL17142945 | 0.84 | KMT2A (0.48) | SMN1; SMN2KMT2ACCNA2CDK2RAB9A | |
| SCHEMBL17148201 | 0.84 | KMT2A (0.55) | SMN1; SMN2KMT2AMAPTPOLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |