Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148296 | 0.90 | KIT (0.46) | KMT2AMCHR1CYP1A2SMN1; SMN2CDK1 | |
| SCHEMBL17148171 | 0.90 | CDK1 (0.45) | KMT2AMCHR1CYP1A2SMN1; SMN2CDK1 | |
| SCHEMBL17148262 | 0.89 | ALDH1A1 (0.43) | KMT2AALDH1A1KDM4EMCHR1MEN1 | |
| SCHEMBL17148246 | 0.88 | KMT2A (0.52) | KMT2AALDH1A1MEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL17142461 | 0.85 | MCHR1 (0.50) | KMT2AALDH1A1KDM4EHSD17B10MCHR1 | |
| SCHEMBL17148252 | 0.85 | GRM4 (0.53) | KMT2AALDH1A1KDM4EHSD17B10MCHR1 | |
| SCHEMBL17142511 | 0.84 | KMT2A (0.54) | KMT2AALDH1A1CYP1A2SMN1; SMN2POLB | |
| SCHEMBL17143130 | 0.83 | KMT2A (0.55) | KMT2AALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL17148175 | 0.83 | EPHX2 (0.45) | KMT2AALDH1A1MCHR1CYP1A2SMN1; SMN2 | |
| SCHEMBL17148354 | 0.83 | KMT2A (0.60) | KMT2AALDH1A1KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |