SCHEMBL1714899

SCHEMBL1714899

c1ccc(-c2c3ccccc3c(-c3ccc(-n4c5ccccc5c5cc(-c6ccc7ccccc7c6)ccc54)cc3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KMT2A Q03164 1/20 0.40
ESR1 P03372 5/20 0.38
ESR2 Q92731 5/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38
TUBB6 Q9BUF5 1/20 0.38
TUBB2B Q9BVA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124862 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL262168 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL13433162 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL13433163 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL13433010 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL261780 0.99 L3MBTL1 (0.49) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL12461545 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL262156 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL13432999 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1
SCHEMBL13433067 0.99 KDM4E (0.45) KDM4EATML3MBTL1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP disclosed
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US disclosed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
CN-101676265-A Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB 2010-03-24 CN disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device CRY1, CHRM1, CYP1A1 KDM4E 3714/4885ATM 2629/4885L3MBTL1 235/4885
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same AADAC, CYP1A1, CYP1B1 KDM4E 3302/4885ATM 1046/4885L3MBTL1 3790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.