SCHEMBL17149255

SCHEMBL17149255

COC(=O)c1cc2cc(-c3ccc(C)cc3)ccc2s1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
F9 P00740 6/20 0.47
F10 P00742 3/20 0.47
ICAM1 P05362 1/20 0.46
SELE P16581 1/20 0.46
VCAM1 P19320 1/20 0.46
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HDAC1 Q13547 2/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17149254 0.88 HDAC1 (0.54) MAPTMEN1KMT2AICAM1SELE
SCHEMBL149464 0.88 F9 (0.58) MAPTMEN1KMT2AF9F10
SCHEMBL31108990 0.88 MEN1 (0.64) MAPTMEN1KMT2AICAM1SELE
SCHEMBL2895953 0.88 MEN1 (0.64) MAPTMEN1KMT2AICAM1SELE
SCHEMBL15697495 0.87 F9 (0.51) MAPTMEN1KMT2AF9F10
SCHEMBL3497047 0.86 BCL2L1 (0.53) MAPTMEN1KMT2AF9F10
SCHEMBL15697567 0.86 MEN1 (0.47) MAPTMEN1KMT2AF9F10
SCHEMBL3500033 0.86 MAPT (0.56) MAPTMEN1KMT2AF9F10
SCHEMBL15697487 0.83 PTPN2 (0.47) MAPTMEN1KMT2AF9F10
SCHEMBL15697562 0.81 CLK1 (0.51) MAPTMEN1KMT2AF9F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9894901-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-20 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B MAPT 3813/4885MEN1 4418/4885KMT2A 1223/4885
US-20150282482-A1 METHOD FOR PROMOTING PLANT GROWTH BOLA2; BOLA2B, BROX, TET1 MAPT 3761/4885MEN1 4448/4885KMT2A 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.