SCHEMBL3497047

SCHEMBL3497047

Cc1ccc(-c2ccc3sc(C(=O)O)cc3c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.53
F9 P00740 4/20 0.51
MCL1 Q07820 1/20 0.50
GPR35 Q9HC97 2/20 0.49
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
CLK1 P49759 2/20 0.45
DYRK1A Q13627 2/20 0.45
DYRK1B Q9Y463 2/20 0.45
F10 P00742 2/20 0.44
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17173215 0.87 HDAC1 (0.54) BCL2L1MCL1GPR35MEN1MAPT
SCHEMBL121331 0.87 F9 (0.67) BCL2L1F9MCL1GPR35MEN1
SCHEMBL22777736 0.87 F9 (0.67) BCL2L1F9MCL1GPR35MEN1
SCHEMBL2801905 0.86 BCL2L1 (0.59) BCL2L1GPR35MEN1MAPTKMT2A
SCHEMBL17149255 0.86 MAPT (0.62) F9MEN1MAPTKMT2ACLK1
SCHEMBL3499370 0.84 BCL2L1 (0.53) BCL2L1F9GPR35CLK1DYRK1A
SCHEMBL3498018 0.84 BCL2L1 (0.53) BCL2L1F9GPR35CLK1DYRK1A
SCHEMBL3500337 0.83 BCL2L1 (0.49) BCL2L1F9GPR35CLK1DYRK1A
SCHEMBL3496932 0.83 CLK1 (0.55) BCL2L1F9CLK1DYRK1ADYRK1B
SCHEMBL15697500 0.83 BCL2L1 (0.51) BCL2L1F9GPR35DYRK1ADYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-27 US disclosed
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-27 US disclosed
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-05-27 US disclosed
EP-1849465-A1 AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR Takeda Pharmaceutical Company Limited (JP) 2007-10-31 EP disclosed
EP-1849465-A1 AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR Takeda Pharmaceutical Company Limited (JP) 2007-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130737-A1 Regulating Agent of GPR34 Receptor Function GPR34, GPR4, GPR6 BCL2L1 2669/4885F9 4781/4885MCL1 3727/4885
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B BCL2L1 2137/4885F9 1446/4885MCL1 4700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.