Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714590 | 0.84 | PTGDR2 (0.68) | PTGDR2TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL1714137 | 0.82 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL14026612 | 0.78 | PTGDR2 (0.68) | PTGDR2NPC1LMNAKDM4EALDH1A1 | |
| SCHEMBL1713829 | 0.77 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL4607574 | 0.76 | PTGDR2 (0.62) | PTGDR2NPC1LMNAKDM4EALDH1A1 | |
| SCHEMBL1714918 | 0.76 | PTGDR2 (0.64) | PTGDR2HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL4609205 | 0.74 | PTGDR2 (0.63) | PTGDR2NPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL4102165 | 0.72 | PTGDR2 (0.70) | PTGDR2TSHRLMNAKDM4EALDH1A1 | |
| SCHEMBL6738518 | 0.72 | TSHR (0.96) | NPC1HPGDTSHRKDM4EALDH1A1 | |
| SCHEMBL735675 | 0.71 | TSHR (0.81) | NPC1HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | PTGDR2 236/4885NPC1 2530/4885HPGD 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.