Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713019 | 0.95 | PTGDR2 (0.67) | PTGDR2KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1714590 | 0.87 | PTGDR2 (0.68) | PTGDR2KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1714387 | 0.82 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1TP53 | |
| SCHEMBL9975978 | 0.80 | KDM4E (0.65) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL27712891 | 0.78 | PTGDR2 (0.73) | PTGDR2KDM4EALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28770778 | 0.78 | PTGDR2 (0.69) | PTGDR2KDM4EALDH1A1MAPTGAA | |
| SCHEMBL1714744 | 0.78 | LMNA (0.81) | KDM4EALDH1A1MAPTGAAHTT | |
| SCHEMBL27712886 | 0.77 | PTGDR2 (0.71) | PTGDR2SMN1; SMN2L3MBTL1TSHRMEN1 | |
| SCHEMBL27693139 | 0.77 | PTGDR2 (0.71) | PTGDR2SMN1; SMN2L3MBTL1TSHRMEN1 | |
| SCHEMBL13800181 | 0.77 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | PTGDR2 236/4885KDM4E 1277/4885ALDH1A1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.