Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDXK | O00764 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005156 | 0.85 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3AOC3KDM4E | |
| SCHEMBL5552108 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3AOC3KDM4E | |
| SCHEMBL15382533 | 0.76 | UHRF1 (0.45) | SLC6A2SLC6A4SLC6A3AOC3KDM4E | |
| SCHEMBL11013326 | 0.76 | KDM4E (0.45) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL25652153 | 0.75 | NOS3 (0.42) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11468401 | 0.74 | KDM4E (0.44) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL19824289 | 0.74 | UHRF1 (0.41) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL20676684 | 0.73 | KDM4E (0.46) | SLC6A2SLC6A4SLC6A3KDM4ETSHR | |
| SCHEMBL18986020 | 0.73 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3AOC3KDM4E | |
| SCHEMBL5013477 | 0.72 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015152368-A1 | OXAZOLIDINONE AND OXAZINANONE DERIVATIVES | 大正製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |